Anti-apoptotic gene transcription signature of salivary gland neoplasms
نویسندگان
چکیده
منابع مشابه
Review of Salivary Gland Neoplasms
Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a...
متن کاملTP53 mutations in salivary gland neoplasms.
Many studies have demonstrated that loss of TP53 gene function has an important role in the genesis of many neoplasms, including salivary gland neoplasms. The purpose of this study was to examine the mutation profile of the TP53 gene in salivary gland neoplasms. Genomic DNA was extracted from paraffin-embedded tissues of pleomorphic adenoma, carcinoma in pleomorphic adenoma, mucoepidermoid carc...
متن کاملHeterologous Anti-Salivary Gland Antibodies
The purpose of the present study was to investigate the possibility of experimental induction of sialadenitis in rats by heterologous anti-salivary gland antibodies. Two fractiens (Fractions I and II) were separated from rat submaxillary gland by SephadexG 200 gel-filtration, and then rabbits were immunized with each fraction. Although cross-reactivitv of anti-Frl antiscrum obtained from the ra...
متن کاملD-1 Gene Polymorphism in Salivary Gland Tumors
Objectives This study aimed to assess PD-1gene polymorphism in salivary gland tumors in patients referred to Khalili Hospital in Shiraz. Methods This case-control study evaluated 48 patients with salivary gland tumors and 100 age- and sex-matched healthy controls. First, 5cc blood samples were obtained from patients and transferred to vials containing anti-coagulated EDTA. DNA was extracted, a...
متن کامل[Epidemiologic profile of salivary gland neoplasms: analysis of 245 cases].
AIM The aim of the present study is to establish the relative frequency and distribution of benign and malignant epithelial neoplasms of salivary glands in the Pathology and Cytology Laboratory, STUDY DESIGN Historic cohort. MATERIAL AND METHOD in the state of Sergipe, during the period 1980-1999. The neoplasms were individualized by gender, age, race of the patients, anatomic localization ...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2012
ISSN: 1471-2407
DOI: 10.1186/1471-2407-12-61